Zebrafish miRNA expression profiles. Development (A) and mature tissue (B) expression profiles generated by MeV 4.0 software using normalized reads number of each miRNA are shown. Some miRNAs were mainly expressed during development, namely dre-miR-430 family, dre-miR-135c and dre-miR-9. The former was absent in the adult fish while dre-miR-135c and dre-miR-9 had decreased expression in mature organs with exception of the brain. Conversely, dre-miR-124, dre-let-7a and dre-mir-21 were ubiquitously expressed. Dre-miR-499 was heart specific, dre-miR-1 and dre-miR-133a were detected in both muscle and heart and dre-miR-103 and dre-miR-122 were gut/liver specific.
Soares et al. BMC Genomics 2009 10:195 doi:10.1186/1471-2164-10-195