Genomic organisation of the genes in the bovine TRB locus as described in Btau_3.1. The order and location of TRB genes on (A) Chr4.003.105 (B) Chr.4.003.108_RC and (C) ChrUn.003.1717. Red dotted lines represent large regions of undetermined sequence within the scaffolds. TRBV genes are classified as functional (green), open-reading frame non-functional (orange) or pseudogenes (red), and their transcriptional orientation indicated by their direction; TRBV gene 'relics' are shown as open boxes. TRBD (blue vertical lines), TRBJ (pink vertical lines) and TRBC (yellow boxes) genes are arranged into 3 DJC clusters, with a putative bovine TRB enhancer (Eβ) located 3' to the TRBC3 gene (black diagonal shading). The sizes of non TRB genes (black boxes) – dopamine-β-hydroxylase-like gene (DβH-like) and trypsinogen genes (T) are not shown to scale. Regions of duplicated DNA are indicated by the colour-coordinated boxes located beneath the scheme of gene location. Broken lines indicate regions of DNA that are not present in all copies of the duplicated region.
Connelley et al. BMC Genomics 2009 10:192 doi:10.1186/1471-2164-10-192