Table 6 |
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|
Genes with putative cummulative downregulation in blastocysts obtained after serial rounds of chromatin tranfer |
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|
Probe Set ID |
Gene Title |
Gene Symbol |
IVF |
CT1 |
CT4 |
Fold change IVF/CT1 |
Fold change IVF/CT4 |
|
|
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|
Bt.5154.1.S1_at |
heat shock 70 kD protein 1 |
HSPA1A |
16655.53 |
4021.00 |
2975.26 |
4.14 |
5.60 |
|
Bt.9759.1.S1_a_at |
neuroguidin, EIF4E binding protein |
NGDN |
11691.84 |
5346.60 |
3041.70 |
2.19 |
3.84 |
|
Bt.5039.1.S1_at |
high mobility group nucleosomal binding domain 3 |
HMGN3 |
11195.32 |
6522.85 |
4078.53 |
1.72 |
2.74 |
|
Bt.9759.2.S1_at |
neuroguidin, EIF4E binding protein |
NGDN |
5999.87 |
2431.02 |
1665.35 |
2.47 |
3.60 |
|
Bt.4737.1.S2_s_at |
prion protein |
PRNP |
3552.73 |
1614.40 |
1425.30 |
2.20 |
2.49 |
|
Bt.1854.1.S1_at |
intraflagellar transport protein 20 |
IFT20 |
3526.47 |
2139.25 |
1380.10 |
1.65 |
2.56 |
|
Bt.27874.1.S1_s_at |
phosphatidylserine receptor |
PTDSR |
3476.73 |
1517.25 |
980.58 |
2.29 |
3.55 |
|
Bt.15787.1.S1_at |
Bcl-2 inhibitor of transcription |
BIT1 |
2989.58 |
2007.15 |
1415.27 |
1.49 |
2.11 |
|
Bt.20204.1.S1_at |
Sjogren's syndrome/scleroderma autoantigen 1 |
SSSCA1 |
1695.08 |
1056.05 |
579.62 |
1.61 |
2.92 |
|
Bt.4595.1.S1_at |
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
TSR2 |
1567.39 |
755.35 |
568.11 |
2.08 |
2.76 |
|
Bt.12250.1.S1_at |
chromosome 14 open reading frame 10 |
C14orf10 |
1525.13 |
981.80 |
567.59 |
1.55 |
2.69 |
|
Bt.27095.1.S1_at |
collaborates/cooperates with ARF (alternate reading frame) protein |
CARF |
1390.25 |
907.40 |
668.85 |
1.53 |
2.08 |
|
Bt.13928.2.S1_a_at |
sodium channel modifier 1 |
SCNM1 |
786.05 |
390.50 |
249.35 |
2.01 |
3.15 |
|
Bt.6620.1.S1_at |
myosin, heavy polypeptide 7, cardiac muscle, beta |
MYH7 |
673.53 |
219.15 |
135.85 |
3.07 |
4.96 |
|
Bt.19972.1.S1_at |
proton-dependent gastrointestinal peptide transporter |
PEPT1 |
567.85 |
189.46 |
170.27 |
3.00 |
3.34 |
|
Bt.28010.1.S1_at |
protease inhibitor 3, skin-derived (SKALP) |
PI3 |
510.98 |
91.50 |
56.05 |
5.58 |
9.12 |
|
Bt.5126.1.S1_at |
hypertension-related calcium-regulated gene |
COMMD5 |
449.40 |
335.50 |
176.24 |
1.34 |
2.55 |
|
Bt.22523.1.S1_at |
dispatched homolog 1 (Drosophila) |
DISP1 |
402.17 |
174.75 |
155.13 |
2.30 |
2.59 |
|
Bt.5828.1.S1_at |
SERTA domain containing 1 |
SERTAD1 |
357.71 |
287.95 |
157.44 |
1.24 |
2.27 |
|
Bt.333.1.S1_at |
transition protein 1 (during histone to protamine replacement) |
TNP1 |
233.38 |
155.00 |
98.93 |
1.51 |
2.36 |
|
Bt.14098.1.S1_at |
microtubule-associated protein, RP/EB family, member 2 |
MAPRE2 |
199.89 |
183.45 |
69.82 |
1.09 |
2.86 |
|
Bt.4158.1.A1_at |
oviduct specific glycoprotein |
OVGP1 |
196.48 |
168.70 |
78.09 |
1.16 |
2.52 |
|
Bt.22856.1.S1_at |
neurofilament, medium polypeptide |
NEF3 |
188.69 |
126.35 |
46.89 |
1.49 |
4.02 |
|
Bt.9807.1.S1_at |
glycoprotein (transmembrane) nmb |
GPNMB |
154.95 |
52.30 |
24.03 |
2.96 |
6.45 |
|
Bt.23151.1.S1_at |
fucosyltransferase 10 (alpha (1,3) fucosyltransferase) |
FUT10 |
154.43 |
114.10 |
55.12 |
1.35 |
2.80 |
|
Bt.7239.1.S1_at |
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 |
SLC6A3 |
149.32 |
48.30 |
21.24 |
3.09 |
7.03 |
|
Bt.12739.2.S1_a_at |
membrane-associated ring finger (C3HC4) 2 |
C3HC4 |
110.18 |
51.40 |
23.87 |
2.14 |
4.62 |
|
Bt.6556.1.S1_at |
regakine-1 protein |
LOC504773 |
89.66 |
25.75 |
39.07 |
3.48 |
2.29 |
|
Bt.12080.2.S1_at |
Bernardinelli-Seip congenital lipodystrophy 2 |
BSCL2 |
88.59 |
38.70 |
13.83 |
2.29 |
6.41 |
|
Bt.13036.1.S1_at |
progesterone receptor |
PGR |
79.73 |
4.69 |
36.57 |
17.02 |
2.18 |
|
Bt.2157.1.S1_a_at |
RPGR-interacting protein 1 |
RPGRIP1 |
77.03 |
58.90 |
6.56 |
1.31 |
11.75 |
|
Bt.28409.2.S1_at |
DNA replication factor |
CDT1 |
71.69 |
55.20 |
12.73 |
1.30 |
5.63 |
|
Bt.3771.1.A1_at |
Nucleolar protein family A, member 1 |
NOLA1 |
69.73 |
21.50 |
21.26 |
3.24 |
3.28 |
|
Bt.27752.1.S1_at |
tensin 4 |
TNS4 |
69.66 |
43.05 |
8.73 |
1.62 |
7.98 |
|
Bt.13024.2.S1_at |
purinergic receptor P2Y G-protein coupled, 2 |
P2RY2 |
67.08 |
46.15 |
22.11 |
1.45 |
3.03 |
|
Bt.28017.1.S1_at |
vacuolar H+-ATPase |
LOC407191 |
65.07 |
34.20 |
17.47 |
1.90 |
3.73 |
|
Bt.512.1.S1_at |
nucleotide phosphodiesterase, 3'-5'-cyclic |
PDE1A |
60.70 |
15.59 |
15.85 |
3.89 |
3.83 |
|
Bt.12928.1.S1_at |
Interleukin 13 |
IL13 |
58.85 |
37.70 |
9.25 |
1.56 |
6.36 |
|
Bt.29129.1.S1_at |
anterior gradient 2 homologue |
agr2 |
45.07 |
39.00 |
21.29 |
1.16 |
2.12 |
|
|
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|
(P < 0.01). |
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|
Rodriguez-Osorio et al. BMC Genomics 2009 10:190 doi:10.1186/1471-2164-10-190 |
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