BMC Genomics

official impact factor 4.21

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Estimating accuracy of RNA-Seq and microarrays with proteomics

Xing Fu, Ning Fu, Song Guo, Zheng Yan, Ying Xu, Hao Hu, Corinna Menzel, Wei Chen*, Yixue Li, Rong Zeng and Philipp Khaitovich*

BMC Genomics 2009, 10:161 doi:10.1186/1471-2164-10-161

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Software   Open Access

NanoStriDE: normalization and differential expression analysis of NanoString nCounter data

Christopher D Brumbaugh, Hyunsung J Kim, Mario Giovacchini, Nader Pourmand BMC Bioinformatics 2011, 12:479 (16 December 2011)

Methodology article   Open Access Highly Accessed

Construction and evaluation of a whole genome microarray of Chlamydomonas reinhardtii

Jörg Toepel, Stefan P Albaum, Samuel Arvidsson, Alexander Goesmann, Marco la Russa, Kristin Rogge, Olaf Kruse BMC Genomics 2011, 12:579 (25 November 2011)

Research article   Open Access Highly Accessed

Exploring the gonad transcriptome of two extreme male pigs with RNA-seq

Anna Esteve-Codina, Robert Kofler, Nicola Palmieri, Giovanni Bussotti, Cedric Notredame, Miguel Pérez-Enciso BMC Genomics 2011, 12:552 (8 November 2011)

Research article   Open Access Highly Accessed

Functional annotation of the transcriptome of Sorghum bicolor in response to osmotic stress and abscisic acid

Diana V Dugas, Marcela K Monaco, Andrew Olson, Robert R Klein, Sunita Kumari, Doreen Ware, Patricia E Klein BMC Genomics 2011, 12:514 (18 October 2011)

Review   Open Access Highly Accessed

Microarrays, deep sequencing and the true measure of the transcriptome

John H Malone, Brian Oliver BMC Biology 2011, 9:34 (31 May 2011)

Global measures of gene expression can now be extracted either from microarrays or from RNA-seq, which do not always seem to give the same answer. Malone and Oliver review the advantages and limitations of each and conclude that, with some important exceptions, they tell the same story.

Research article   Open Access Highly Accessed

Integrated network analysis of transcriptomic and proteomic data in psoriasis

Eleonora Piruzian, Sergey Bruskin, Alex Ishkin, Rustam Abdeev, Sergey Moshkovskii, Stanislav Melnik, Yuri Nikolsky, Tatiana Nikolskaya BMC Systems Biology 2010, 4:41 (8 April 2010)

Method   Open Access Highly Accessed

Gene ontology analysis for RNA-seq: accounting for selection bias

Matthew D Young, Matthew J Wakefield, Gordon K Smyth, Alicia Oshlack Genome Biology 2010, 11:R14 (4 February 2010)

GOseq is a method for GO analysis of RNA-seq data that takes into account the length bias inherent in RNA-seq