Table 3

Summary of results concerning circadian genes

C57BL/6J

C57.YA

Interaction

Gene Symbol

Gene Name

FC

FDR

FC

FDR

FDR

Arntl

aryl hydrocarbon receptor nuclear translocator-like

-1.10

0.531

-5.30

0.000

0.006

Dbp

D site albumin promoter binding protein

-1.05

0.772

2.94

0.000

0.006

Tef

thyrotroph embryonic factor

1.02

0.851

2.16

0.001

0.008

Per2

period homolog 2 (Drosophila)

1.11

0.531

2.95

0.001

0.009

Cry2

cryptochrome 2 (photolyase-like)

-1.08

0.370

1.42

0.001

0.019

Clock

circadian locomoter output cycles kaput

-1.10

0.284

-1.62

0.001

0.024

Nr1d2

nuclear receptor subfamily 1, group D, member 2

1.08

0.561

1.84

0.001

0.033

Per3

period homolog 3 (Drosophila)

1.08

0.503

1.67

0.001

0.034

Rora

RAR-related orphan receptor alpha

1.02

0.845

1.46

0.002

0.081

Per1

period homolog 1 (Drosophila)

-1.01

0.923

1.92

0.004

0.087

Csnk1e

casein kinase 1, epsilon

1.02

0.826

1.23

0.016

0.230

Csnk1d

casein kinase 1, delta

1.04

0.789

1.23

0.061

0.437

Nr1d1

nuclear receptor subfamily 1, group D, member 1

-1.36

0.017

-1.39

0.006

0.920

Bhlhb2

basic helix-loop-helix domain containing, class B2

1.14

0.251

1.15

0.135

0.942

Genes were considered as "circadian" on the basis of information from both the KEGG pathway database and additional annotation from the literature. FC: fold change of CX over Sham operated animals; FDR: P-values for the interaction between strain and treatment effects after adjustment for multiple comparisons with an FDR transformation (see methods); FDR values < 0.1 are formatted in bold.

Llamas et al. BMC Genomics 2009 10:150   doi:10.1186/1471-2164-10-150