Table 7

Additional list of three-copy genes that are over-expressed in the external granule cell layer of Ts1Cje as compared to euploid at P0 (q > 0.05)

SYMBOL

Ratio

p-value

q-value

Chr

GO biological process category

Girk2

1.58

0,000

0,109

16

potassium ion transport

Son

1.48

0,001

0,206

16

Cryzl1

1.4

0,000

0,084

16

zinc ion binding

Gart

1.37

0,000

0,080

16

purine nucleotide biosynthetic process

Olig1

1.37

0,048

0,996

16

neuron fate commitment

Donson

1.34

0,000

0,109

16

multicellular organismal development

Dscr3

1.33

0,001

0,238

16

vacuolar transport

Olig2

1.3

0,002

0,343

16

neuron fate commitment

Hmgn1

1.28

0,000

0,109

16

establishment and/or maintenance of chromatin architecture

Cbr3

1.25

0,030

0,996

16

metabolic process

Prdm15

1.23

0,002

0,331

16

Ifnar2

1.16

0,019

0,996

16

cell proliferation

Twelve three-copy genes were found significantly differentially expressed by Student t-test (p < 0.05) but failed the False Discovery Rate controlling procedure of Benjamini and Hochberg (q > 0.05).

Laffaire et al. BMC Genomics 2009 10:138   doi:10.1186/1471-2164-10-138