Research article
Natural genetic variation in transcriptome reflects network structure inferred with major effect mutations: insulin/TOR and associated phenotypes in Drosophila melanogaster
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* Corresponding author: Sergey V Nuzhdin snuzhdin@usc.edu
1 Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089, USA
2 University of Florida Genetics Institute, University of Florida, Gainesville FL 32610-36103, USA
3 School of Biological Sciences, University of Nebraska at Lincoln, Lincoln, NE 68588, USA
BMC Genomics 2009, 10:124 doi:10.1186/1471-2164-10-124
Published: 24 March 2009Additional files
Additional File 1:
Male breeding values for transcript levels in the 9 parental genotypes.
Format: CSV Size: 314KB Download file
Additional File 2:
Female breeding values for transcript levels in the 9 parental genotypes.
Format: CSV Size: 315KB Download file
Additional File 3:
All pairwise correlations between the transcript levels of the genes in Figure1, between transcript levels and phenotypes, or between factors and phenotypes for females (worksheet 1) and males (worksheet 2).
Format: XLS Size: 178KB Download file
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Additional File 4:
The loading values of each gene onto each of the eight possible factors in males and females and a set of indicator variables to indicate whether a gene was considered to load onto a factor as well as a set of indicator variables for genes that load on the same factor in both sexes.
Format: XLS Size: 445KB Download file
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Additional File 5:
Lists all of the significantly enriched (P < 0.01, FDR < 0.15) GO biological process (BP) and molecular function (MF) terms associated with factors 1, 2 and 3 for females (F) and males (M).
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Additional File 6:
Pairwise correlations between AKT or dFOXO and genes reported by ChIP-chip[10]to bind todFOXO.
Format: XLS Size: 155KB Download file
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