Table 2

Stress related genes down regulated in a tra1SRR3413 background.

Gene
Fold-decrease1
Description2

AAD4
11
Putative aryl-alcohol dehydrogenase. Involved in oxidative stress response.
TSA2
6.5
Stress induced thioredoxin peroxidase.
CCS1
5.5
Copper chaperone for superoxide dismutase Sod1. Involved in oxidative stress protection.
AAD6
4.4
Putative aryl-alcohol dehydrogenase. Involved in oxidative stress response.
GPX2
3.6
Phospholipid hydroperoxide glutathione peroxidase. Protects cells from peroxides.
SSA4
3.3
Heat shock protein that is highly induced upon stress. Role in SRP-dependent cotranslational protein-membrane targeting.
GRX2
3.1
Glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase. Maintains redox state of target proteins.
RHR2
3.0
DL-glycerol-3-phosphatase. Induced by anaerobic and osmotic stress.
ALD2
2.4
Aldehyde dehydrogenase. Stress induced.
TRX2
2.4
Thioredoxin isoenzyme. Protects cells against oxidative stress.
GRE2
2.4
3-methylbutanal reductase and methylglyoxal reductase. Stress induced.
SRX1
2.4
Sulfiredoxin. Contributes to oxidative stress resistance.
ALD3
2.3
Cytoplasmic aldehyde dehydrogenase. Stress induced.
LSP1
2.3
Component of eisosomes. Null mutants show activation of Pkc1p/Ypk1p stress pathways.
PST2
2.2
Similarity to flavodoxin-like proteins. Induced by oxidative stress.
CMK1
2.2
Calmodulin-dependent protein kinase. May play a role in stress response.
DAK1
2.0
Dihydroxyacetone kinase. Involved in stress adaptation.

1 Decrease in gene expression from microarray analysis [9], tra1SRR3413 versus TRA1

2 Modified from the Saccharomyces Genome Database

Hoke et al. BMC Genetics 2008 9:46   doi:10.1186/1471-2156-9-46