Table 4 |
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|
λS and sib-sib OR (with 95% CI) for pre-eclampsia. |
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|
All races |
White |
Black |
|
|
|
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|
Population: pre-eclampsia |
8600 |
6749 |
1736 |
|
Population: N |
267840 |
220505 |
42861 |
|
Population risk |
0.032 (0.031–0.033) |
0.031 (0.031–0.031) |
0.041 (0.039–0.043) |
|
Siblings: sibpairs with both siblings affected |
1070 |
821 |
233 |
|
Siblings: sibpairs with first sibling affected |
7384 |
5869 |
1400 |
|
Sibling risk |
0.145 (0.137–0.153) |
0.140 (0.131–0.149) |
0.166 (0.146–0.186) |
|
λS |
4.5 (4.2–4.8) |
4.5 (4.2–4.8) |
4.1 (3.6–4.6) |
|
Sib-sib unadjusted OR (95% CI) |
9.2 (8.5–9.9) |
10.0 (9.1–10.9) |
6.7 (5.7–7.9) |
|
Sib-sib adjusted OR (95% CI)# |
8.1 (7.5–8.8) |
9.0 (8.2–9.8) |
5.8 (4.9–7.0) |
|
|
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|
#Adjusted for mother < 20 or > 35 years old, mother < 12 education, Medicaid (index of low SES), no prenatal care, mother BMI < 20 kg/m2, cigarette smoking, insulin-dependent diabetes mellitus, chronic hypertension |
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Plunkett et al. BMC Genetics 2008 9:44 doi:10.1186/1471-2156-9-44 |
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