|
Clinical characteristics of the study population |
|||
| Characteristics |
DMa (n = 225) |
CRIb (n = 196) |
P |
|
|
|||
| Gender (M/F) |
76/149 |
65/131 |
0.89d |
| Age (years) |
60.6 ± 11.5 |
57 ± 12.8 |
0.10c |
| BMI (kg/m2) |
23.1 ± 0.3 |
23.4 ± 0.2 |
0.00 |
| Duration of Diabetes (years) |
17.07 ± 6.69 |
10.4 ± 7.7 |
<0.05c |
| Hb A1c (%) |
7.3 ± 1.0 |
7.5 ± 1.1 |
0.949c |
| Systolic pressure (mm Hg) * |
140 (106–190) |
150 (110–210) |
0.002e |
| Diastolic pressure (mm Hg) * |
84 (80–104) |
90 (70–110) |
0.025e |
| Serum creatinine (μmol/l) * |
84 (35–108) |
177 (124–1112) |
<<0.05e |
| UAER (mg/liter)* |
10 (1–16) |
864 (320–1584) |
<<0.05e |
| GFR (mls/min/1.73 m2) |
81.44 ± 21.85 |
27.83 ± 24 |
<<0.05c |
| Serum triglyceride (mmol/l) |
1.7 ± 0.67 |
1.8 ± 1.4 |
0.307c |
| Serum cholesterol (mmol/l) |
4.8 ± 0.97 |
4.9 ± 0.92 |
0.852c |
| Retinopathy (%) Non-proliferative (%) Proliferative (%) |
24 15 09 |
88 35 53 |
<<0.05d |
| Cardiovascular events (%) |
3 |
8.3 |
|
|
Data presented as mean ± SD (* median and range). atype-2 diabetes subjects without nephropathy (DM); b with diabetic renal insufficiency (CRI); c Student's t test; d Pearson's χ2 test; e Mann-Whitney U test. | |||
Prasad et al. BMC Genetics 2008 9:26 doi:10.1186/1471-2156-9-26 |
|||