|
Genotype association between rs7162140 and quantitative measures of substance dependence. |
|||||
| n |
Mean |
SD |
Model |
p-Value (two-tailed) |
|
|
|
|||||
| Tobacco Dose |
|||||
| CC |
192 |
74.9 |
55.1 |
Dominant |
0.01 |
| CT |
73 |
97.0 |
70.9 |
Recessive |
0.84 |
| TT |
8 |
76.6 |
35.8 |
||
| CT|TT |
81 |
95.0 |
68.4 |
||
|
|
|||||
| Alcohol Dose |
|||||
| CC |
354 |
20.1 |
21.8 |
Dominant |
0.81 |
| CT |
161 |
21.1 |
21.1 |
Recessive |
0.41 |
| TT |
21 |
16.4 |
16.2 |
||
| CT|TT |
182 |
20.6 |
20.7 |
||
|
Alcohol dose described as units (10 g) per week. Tobacco dose described as cigarettes smoked per week. Analysis based on both dominant (TT|CT > CC) and recessive (TT > CT|CC) inheritance models using the Student's t-test (two-tailed) to measure equality of means. | |||||
Anney et al. BMC Genetics 2007 8:46 doi:10.1186/1471-2156-8-46 |
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