|
Genotype associations between rs7162140 and categorical measures of substance dependence. |
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| Genotype Count |
|||||
| Case |
Control |
Model |
Odds Ratio |
p-Value |
|
|
|
|||||
| Nicotine Dependence |
|||||
| CC |
48 |
144 |
Dominant |
1.6 (0.90–2.8) |
0.11 |
| CT |
24 |
49 |
Recessive |
2.6 (0.65–11.0) |
0.17 |
| TT |
4 |
4 |
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|
|
|||||
| Alcohol Dependence |
|||||
| CC |
310 |
50 |
Dominant |
1.3 (0.77–2.0) |
0.36 |
| CT |
135 |
28 |
Recessive |
0.95 (0.27–3.3) |
0.94 |
| TT |
18 |
3 |
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|
|
|||||
| Cannabis Dependence |
|||||
| CC |
40 |
19 |
Dominant |
2.9 (1.1–7.4) |
0.03 |
| CT |
9 |
13 |
Recessive |
1.5 (0.20–11.4) |
0.68 |
| TT |
2 |
2 |
|||
|
Odds ratio shown with 95% confidence intervals. Analysis based on both dominant (TT|CT > CC) and recessive (TT > CT|CC) inheritance models. | |||||
Anney et al. BMC Genetics 2007 8:46 doi:10.1186/1471-2156-8-46 |
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