|
Summary of significant findings of GSMA and CPMM |
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| chromosome |
GSMA |
CPMM |
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| 30 cM bin |
previous reports |
location |
SR analysis |
MC-Replications n (%) from 333* |
p-value for whole chromosome |
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|
|
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| pSR |
pSR-weight |
SR* |
Ranks* |
< 1% |
1%–5% |
5%–10% |
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|
|
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| 1 |
3th |
Hicks (LOD = 4.9) |
58 – 87 cM |
0.498 |
0.661 |
298 |
8 – 118 |
-- |
-- |
-- |
0.007 |
| 4th |
87 – 116 cM |
0.050 |
0.055 |
430 |
51 – 117 |
-- |
333 100% |
-- |
|||
| 2 |
4th |
Martinez (MLS = 2.0) |
89 – 120 cM |
0.220 |
0.147 |
358 |
39 – 115 |
-- |
-- |
-- |
0.250 |
| 5th |
120 – 149 cM |
0.183 |
0.096 |
368 |
7 – 118 |
-- |
-- |
8 2% |
|||
| 7th |
Pankratz (LOD = 2.5) |
179 – 209 cM |
0.447 |
0.427 |
308 |
51 – 73 |
-- |
-- |
-- |
||
| 5 |
5th |
Hicks (LOD = 1.6) |
113 – 141 cM |
0.094 |
0.099 |
399 |
49 – 125 |
-- |
18 5% |
315 95% |
0.108 |
| 6th |
Scott (MLOD = 2.4) |
142 – 169 cM |
0.036 |
0.034 |
506 |
51 – 118 |
-- |
333 100% |
-- |
||
| 3rd-60 cM |
Martinez (MLS = 1.1) |
132 – 198 cM |
0.019 |
0.014 |
224.5 |
24.5 – 58 |
-- |
304 91% |
29 9% |
||
| 8 |
1st |
Scott (MLOD = 2.0) |
0 – 28 cM |
0.131 |
0.208 |
384.5 |
14.5 – 117 |
-- |
-- |
-- |
0.331 |
| 9 |
6th |
DeStefano (MLS = 1.3) |
140 – 169 cM |
0.015 |
0.012 |
461 |
55 – 114 |
-- |
333 100% |
-- |
0.321 |
| 3rd-60 cM |
112 – 169 cM |
0.035 |
0.238 |
215 |
16 – 58 |
-- |
332 99% |
1 <1% |
|||
| 14 |
5th |
110 – 138 cM |
0.036 |
0.047 |
434 |
51 – 115 |
-- |
333 100% |
0.300 |
||
| X |
Pankratz (LOD = 2.5) |
---- not in GSMA analysis --- |
0.002 |
||||||||
|
* for 30 cM bin analysis: SR ranges from 5 to 590, ranks are ranging from 1 to 118 for 60 cM bin analysis: SR ranges from 5 to 290, ranks are ranging from 1 to 58. ** Remaining replications show p ≥ 10% Chromosomes 2 and 8 are listed, because findings therefore have been reported by individual scans. | |||||||||||
Rosenberger et al. BMC Genetics 2007 8:44 doi:10.1186/1471-2156-8-44 |
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