|
DXMit16 Genotype frequency in 3 week old CF and non-CF mice of replicate studies |
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| dataset |
No. mice |
No. B6:B6 |
No. B6:BALB |
No. BALB:BALB |
P-valuec |
|
|
|
||||||
| F2 Non-CF 3 weeks |
||||||
| Females |
Presenta |
687 |
210 |
188 |
289 |
3.0 × 10-35 |
| HSCb |
45 |
5 |
23 |
17 |
0.04 |
|
| total |
732 |
215 |
211 |
306 |
3.8 × 10-34 |
|
| Males |
Present |
341 |
154d |
0 |
187 |
0.05 |
| HSC |
51 |
17 |
0 |
34 |
7.6 × 10-4 |
|
| total |
392 |
171 |
0 |
221 |
0.012 |
|
| F2 CF 3 weeks |
||||||
| Females |
Present |
56 |
14 |
31 |
11 |
0.62 |
| HSC |
134 |
32 |
75 |
27 |
0.32 |
|
| total |
190 |
46 |
106 |
38 |
0.20 |
|
| Males |
Present |
79 |
34 |
0 |
45 |
0.22 |
| HSC |
126 |
79 |
0 |
47 |
5.5 × 10-5 |
|
| total |
205 |
113 |
0 |
92 |
0.14 |
|
|
aPresent data set; bData taken from Haston & Tsui 2003, from the Hospital for Sick Children. cP-values obtained by standard Pearson's χ2 test comparing observed values to expected 1:2:1 ratio (B6/B6:B6/BALB:BALB/BALB) of genotypes, (except for 1:1 X chromosome genotypes of male mice). B6 = C57BL/6J, BALB = BALB/cJ. dDXMit16 genotype is B6 or BALB in male mice. | ||||||
Haston et al. BMC Genetics 2007 8:23 doi:10.1186/1471-2156-8-23 |
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