Table 1

Genotype frequency in 3 week old B6 × BALB F2 CF and non-CF mice

Marker
 Position (Mb)a
 No. mice
 No. B6:B6
 No. B6:BALB
 No. BALB:BALB
 P-valueb
F2 Non-CF 3 weeks
Females
 D5Mit239
 107.7
 707
 145
 292
 270
 5.7 × 10-15

DXMit16
 95.6
 687
 210
 188
 289
 3.0 × 10-35

D3Mit189
 101.1
 367
 101
 171
 95
 0.39
Males
 D5Mit239
 107.7
 358
 74
 192
 92
 0.16

DXMit16
 95.6
 341
 154c
 0
 187
 0.07

D3Mit189
 101.1
 364
 98
 176
 90
 0.69
F2 CF 3 weeks
Females
 D5Mit239
 107.7
 58
 9
 30
 19
 0.17

DXMit16
 95.6
 56
 14
 31
 11
 0.62

D3Mit189
 101.1
 54
 16
 23
 15
 0.54
Males
 D5Mit239
 107.7
 75
 9
 45
 20
 0.035

DXMit16
 95.6
 79
 35
 0
 43
 0.37

D3Mit189
 101.1
 75
 15
 40
 20
 0.61

ataken from the Ensembl database, release 40, August 2006.

bP-values obtained by standard Pearson's χ2 test comparing observed values to expected 1:2:1 ratio (B6/B6:B6/BALB:BALB/BALB) of genotypes (except for 1:1 X chromosome genotypes of male mice). B6 = C57BL/6J, BALB = BALB/cJ.

c DXMit16 genotype is B6 or BALB in male mice.

Haston et al. BMC Genetics 2007 8:23   doi:10.1186/1471-2156-8-23