Volume measures for linkage disequilibrium

doi:10.1186/1471-2156-7-54

BMC Genetics

Volume 7

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Volume measures for linkage disequilibrium

Yuguo Chen¹ , Chia-Ho Lin² and Chiara Sabatti²^,3

¹Department of Statistics, University of Illinois at Urbana-Champaign, Champaign IL 61820, USA

²Department of Statistics, UCLA, Los Angeles CA 90095-1554, USA

³Department of Human Genetics, UCLA, Los Angeles CA 90095-7088, USA

author email corresponding author email

BMC Genetics 2006, 7:54doi:10.1186/1471-2156-7-54


Published:	17 November 2006

Additional files

Additional file 1:

Measures of disequilibrium between biallelic markers. This .pdf file contains a detailed description of measures of disequilibrium for population haplotype distributions for biallelic markers. We recall the definition of D' and R²as well of Dvol and Mvol. We graphically illustrate the difference in normalization procedure between all of these measures. This makes it easy to see the identity of D' and Dvol when the population haplotype frequency is known.

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