Table 1

Bovine PRNP haplotype frequencies in populations of U.S. cattle

Network #1a
 Network #2
 Haplotype frequencies

Haplotype


















n = 188d
 n = 172
 n = 78
 n = 102
 n = 40




















#
 449b
 1392
 1576
 1701
 4136
 4450–4461c
 4732
 4776
 6811
 8631
 9162
 9786
 13793
 13861
 13925
 17284
 20720
 20957
 21680
 Bos taurus
 Holstein
 British
 Continental
 Indicus cpe
1
 T
 C
 C
 G
 C
 Z
 G
 C
 A
 A
 T
 T
 G
 C
 G
 G
 T
 C
 T
 0.102
 -
 0.158
 0.067
 0.125
2
 T
 C
 C
 G
 C
 Z
 G
 C
 A
 A
 T
 T
 G
 C
 C
 G
 C
 C
 C
 0.100
 0.264
 0.083
 0.099
 0.075
3
 G
 C
 C
 A
 C
 I
 A
 T
 A
 G
 T
 C
 A
 G
 C
 G
 C
 C
 C
 0.087
 0.059
 0.044
 0.088
 -
4
 T
 C
 C
 G
 C
 Z
 G
 C
 A
 A
 T
 T
 G
 C
 C
 G
 C
 C
 T
 0.081
 -
 0.075
 0.073
 0.075
5
 T
 C
 C
 G
 C
 Z
 G
 C
 A
 A
 T
 T
 G
 C
 G
 G
 C
 T
 T
 0.071
 0.030
 0.079
 0.029
 -
6
 T
 C
 C
 A
 C
 Z
 G
 C
 A
 G
 T
 T
 A
 C
 C
 G
 C
 C
 T
 0.049
 -
 0.026
 0.078
 0.025
7
 G
 C
 C
 A
 T
 I
 A
 C
 A
 G
 C
 C
 A
 G
 C
 G
 C
 C
 T
 0.033
 -
 0.039
 -
 -
8
 T
 C
 C
 G
 C
 Z
 G
 C
 A
 A
 T
 T
 G
 C
 G
 G
 C
 C
 T
 0.027
 -
 -
 0.069
 -
9
 G
 C
 C
 A
 C
 I
 A
 C
 A
 G
 T
 C
 A
 G
 C
 G
 C
 C
 C
 0.027
 0.042
 0.074
 -
 -
10
 T
 C
 C
 A
 C
 Z
 G
 C
 T
 A
 T
 T
 G
 C
 G
 G
 C
 T
 T
 0.027
 -
 0.026
 0.029
 -
11
 T
 C
 C
 G
 C
 Z
 G
 C
 A
 A
 T
 T
 A
 C
 C
 G
 C
 C
 T
 0.024
 -
 -
 0.029
 -
12
 G
 C
 C
 A
 C
 I
 A
 T
 A
 G
 T
 C
 A
 G
 C
 A
 C
 C
 C
 - f
 0.091
 -
 -
 -
13
 G
 C
 C
 A
 C
 I
 G
 C
 A
 G
 T
 C
 A
 G
 C
 G
 C
 C
 C
 -
 0.084
 -
 -
 -
14
 T
 C
 C
 G
 C
 Z
 G
 C
 A
 A
 T
 T
 A
 G
 C
 G
 C
 C
 C
 -
 0.053
 0.036
 -
 -
15
 T
 C
 C
 G
 C
 Z
 G
 C
 A
 A
 T
 T
 A
 C
 C
 G
 C
 C
 C
 -
 0.052
 -
 -
 -
16
 G
 C
 C
 A
 T
 I
 A
 C
 A
 G
 C
 T
 A
 G
 C
 G
 C
 C
 T
 -
 0.032
 -
 0.029
 -
17
 T
 C
 C
 A
 C
 I
 G
 C
 A
 G
 T
 T
 A
 G
 C
 G
 C
 C
 T
 -
 0.030
 -
 -
 -
18
 G
 T
 C
 A
 T
 I
 A
 C
 A
 G
 T
 T
 A
 C
 C
 G
 C
 C
 T
 -
 -
 -
 0.039
 -
19
 T
 C
 T
 A
 C
 I
 G
 C
 A
 G
 T
 T
 A
 C
 C
 G
 C
 C
 T
 -
 -
 -
 -
 0.123
Total haplotype frequency
 0.628
 0.737
 0.640
 0.629
 0.423

aNetworks 1 and 2 are shown in figure 5.

bNucleotide position in GenBank accession # DQ457195.

cTwelve base InDel, I = GGGGGCCGCGGC, Z = deletion.

dNumber of haploid genomes.

eComposites of U.S. Brahman.

fIndicates 0.000 frequency in population.

Clawson et al. BMC Genetics 2006 7:51   doi:10.1186/1471-2156-7-51