Bovine PRNP haplotypes defined by two Median-Joining networks. Two networks were constructed from 19 htSNPs. Network one was generated from htSNPs 449–6811 (n = 9), and network two from htSNPs 8631–21680 (n = 10). The physical positions of all 19 htSNPs are shown with solid vertical lines along the PRNP physical map. The dashed vertical line shows the position of a non-htSNP at nucleotide 7176 of the PRNP consensus sequence file [GenBank:DQ457195]. Circles represent extant PRNP haplotypes and are not scaled to frequency. Grey rectangles represent PRNP haplotypes not observed in our sample. Sequence for each network combination is presented in Table 1.
Clawson et al. BMC Genetics 2006 7:51 doi:10.1186/1471-2156-7-51