Table 2

Genotype frequencies of the 14 CYP7A1 SNPs in the four HapMap populations.

#

SNP ID

Variation Allele 1/2

CEU

CHB

JPT

YRI

FA2

ObH

HW-p

FA2

ObH

HW-p

FA2

ObH

HW-p

FA2

ObH

HW-p

1

rs10504255

A/G

0.317

0.456

1.0

0.200

0.356

0.886

0.170

0.250

0.694

0.017

0.022

1.0

2

rs10957057

C/T

0.142

0.222

1.0

0.122

0.244

0.999

0.159

0.318

0.586

0.092

0.178

1.0

3

rs8192879

C/T

0.367

0.467

0.754

0.267

0.444

0.663

0.261

0.386

1.0

0.225

0.333

1.0

4

rs11786580

C/T

0.242

0.367

1.0

0.056

0.111

1.0

0.091

0.182

1.0

0.192

0.311

1.0

5

rs3747809

A/G

0

0

0.011

0.022

1.0

0.058

0.116

1.0

0

0

6

rs1457043

T/C

0.392

0.522

0.754

0.567

0.556

0.616

0.625

0.523

0.718

0.575

0.467

0.911

7

rs2162459

A/G

0.392

0.522

0.754

0.567

0.556

0.616

0.625

0.523

0.718

0.583

0.456

1.0

8

rs3808607

T/G

0.367

0.489

1.0

0.411

0.467

0.989

0.570

0.535

0.836

0.583

0.456

1.0

9

rs3824260

G/A

0.367

0.489

1.0

0.411

0.467

0.989

0.570

0.535

0.836

0.550

0.478

0.784

10

rs7833904

T/A

0.408

0.511

1.0

0.622

0.533

0.612

0.663

0.535

0.382

0.558

0.444

0.313

11

rs3903445

G/T

0.408

0.511

1.0

0.622

0.533

0.612

0.648

0.523

0.580

0.550

0.467

0.44

12

rs1125226

A/C

0.398

0.517

1.0

0.622

0.533

0.612

0.663

0.535

0.382

0.575

0.456

0.343

13

rs1023649

A/G

0.415

0.517

1.0

0.622

0.533

0.612

0.648

0.523

0.580

0.575

0.456

0.343

14

rs1023652

C/G

0.408

0.511

1.0

0.433

0.556

0.616

0.314

0.488

0.665

0.125

0.189

0.073

FA2: frequency of allele 2; ObH: observed frequency of heterozygous genotypes; HW-p: Hardy-Weinberg p value.

Nakamoto et al. BMC Genetics 2006 7:29   doi:10.1186/1471-2156-7-29