This article is part of the supplement: Genetic Analysis Workshop 14: Microsatellite and single-nucleotide polymorphism

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Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14

Howard J Edenberg1*, Laura J Bierut2, Paul Boyce3, Manqiu Cao4, Simon Cawley4, Richard Chiles4, Kimberly F Doheny3, Mark Hansen5, Tony Hinrichs2, Kevin Jones6, Mark Kelleher4, Giulia C Kennedy4, Guoying Liu4, Gregory Marcus4, Celeste McBride5, Sarah Shaw Murray5, Arnold Oliphant5, James Pettengill3, Bernice Porjesz6, Elizabeth W Pugh3, John P Rice2, Todd Rubano5, Stu Shannon5, Rhoberta Steeke5, Jay A Tischfield7, Ya Yu Tsai3, Chun Zhang4 and Henri Begleiter6

Author Affiliations

1 Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, 635 Barnhill Drive, Indianapolis, IN, USA

2 Department of Psychiatry, Washington University, 660 South Euclid, St. Louis, MO 63110-1093, USA

3 Center for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA

4 Affymetrix, Inc., 3380 Central Expressway, Santa Clara CA 95051, USA

5 Illumina, Inc., 9885 Towne Centre Drive, San Diego, CA 92121-1975, USA

6 Department of Psychiatry, State University of New York, Downstate Medical Center, 450 Clarkson Avenue Box 1203, Brooklyn, NY 11203-2098, USA

7 Department of Genetics, Rutgers University, 604 Allison Road, Piscataway, NJ 08854-8082, USA

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BMC Genetics 2005, 6(Suppl 1):S2  doi:10.1186/1471-2156-6-S1-S2

Published: 30 December 2005

Abstract

The data provided to the Genetic Analysis Workshop 14 (GAW 14) was the result of a collaboration among several different groups, catalyzed by Elizabeth Pugh from The Center for Inherited Disease Research (CIDR) and the organizers of GAW 14, Jean MacCluer and Laura Almasy. The DNA, phenotypic characterization, and microsatellite genomic survey were provided by the Collaborative Study on the Genetics of Alcoholism (COGA), a nine-site national collaboration funded by the National Institute of Alcohol and Alcoholism (NIAAA) and the National Institute of Drug Abuse (NIDA) with the overarching goal of identifying and characterizing genes that affect the susceptibility to develop alcohol dependence and related phenotypes. CIDR, Affymetrix, and Illumina provided single-nucleotide polymorphism genotyping of a large subset of the COGA subjects. This article briefly describes the dataset that was provided.