Table 1

Distribution of Cftr genotypes in female offspring from breeding Cftr heterozygotes on the B6 and mixed backgrounds.

B6 Background

Mixed Background

Cftr

Observed

Expected

Observed

Expected


+/+

207

175

57

47

+/-

371

350

88

94

-/-

122

175

42

47

P

0.00001 (0.04533)*

0.21724


Statistical analysis was by Chi-square. (*) P-value if the sample size for the B6 mice is adjusted to be equal to that of the mixed background mice, assuming the same distribution of genotypes.

Norkina and De Lisle BMC Genetics 2005 6:29   doi:10.1186/1471-2156-6-29

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