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Open AccessResearch article

Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans

Clive J Petry1 email, Ken K Ong1 email, Bryan J Barratt2 email, Diane Wingate1 email, Heather J Cordell2 email, Susan M Ring3 email, Marcus E Pembrey4 email, The ALSPAC Study Team3 email, Wolf Reik5 email, John A Todd2 email and David B Dunger1 email

Department of Paediatrics, University of Cambridge, Addenbrooke's Hospital Level 8, Box 116, Cambridge CB2 2QQ, UK

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK

Unit of Paediatric and Perinatal Epidemiology, University of Bristol, 24 Tyndall Avenue, Bristol, UK

Clinical and Molecular Genetics Unit, Institute of Child Health, London, UK

Laboratory of Developmental Genetics and Imprinting, Babraham Institute, Cambridge, UK

author email corresponding author email

BMC Genetics 2005, 6:22doi:10.1186/1471-2156-6-22

Published: 10 May 2005

Additional files

Additional File 1:

Birthweight SD score (adjusted for sex and gestational age) by combination of H19 2992/1737/3238 genotypes (for each SNP, 1 = more common homozygote, 2 = heterozygote, 3 = less common homozygote).

Format: PPT Size: 29KB Download file

This file can be viewed with: Microsoft PowerPoint Viewer

Additional File 2:

Schematic map of H19 indicating exons, SNPs published on dbSNP and also published SNPs identified by the Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory (DIL) T1Dbase http://www.t1dbase.org/cgi-bin/welcome.cgi webcite. H19 2992 is indicated by the labels rs217727 and DIL1049.

Format: BMP Size: 2.1MB Download file


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