New RI-like breeding scheme. Novel proposed method for maximizing unique recombinations archived in a 2-way RI-like cross. The breeding scheme shown above and discussed more generally in the text results in a single strain with 75% more unique recombinations than a standard RI strain. This example begins with 7 generations of crosses (parental intercross and F1 × F1 cross not shown) prior to inbreeding. All recombinations generated using this method are independent.
Peirce et al. BMC Genetics 2004 5:7 doi:10.1186/1471-2156-5-7