Table 1

The presence of Ndrg1 and HIF-1α proteins in various normal and malignant human tissues
TISSUE (n)
 Ndrg1
 HIF-1α

-
 +
 ++
 +++
 -
 +
 ++
 +++
Normal Lung (30)
 24
 6
 -
 -
 4
 11
 15
 -
Lung Cancer (30)
 -
 -
 3
 27
 -
 6
 21
 3
Normal Liver (20)
 7
 13
 -
 -
 2
 15
 3
 -
Liver Cancer (20)
 -
 -
 4
 16
 -
 11
 2
 7
Normal Breast (18)
 3
 13
 2
 -
 1
 9
 8
 -
Breast Cancer (20)
 -
 -
 6
 14
 -
 4
 7
 9
Smooth Muscle (30)
 12
 15
 3
 -
 9
 11
 10
 -
S.M. Cancer (24)
 -
 6
 7
 11
 -
 9
 12
 3
Normal Brain (28)
 24
 4
 -
 -
 18
 10
 -
 -
Brain Cancer (36)
 -
 -
 11
 25
 -
 -
 15
 21
Normal Kidney (15)
 -
 6
 8
 1
 -
 5
 10
 -
Kidney Cancer (22)
 -
 -
 7
 15
 -
 7
 9
 6
Normal Skin (20)
 14
 6
 -
 -
 11
 9
 -
 -
Melanoma (10)
 -
 -
 -
 10
 4
 6
 -
 -

Tissues were stained immunohistochemically with antibodies against Ndrg1 and HIF-1α as described in 'Methods' section. Each value shown in the table is from a single tissue sample from an individual patient. The numbers in parentheses (n) represent the total numbers of tissues stained with both antibodies. The expression levels were marked as follows: (-) no staining; (+) weak; (++) moderate; (+++) overexpression.

Cangul BMC Genetics 2004 5:27   doi:10.1186/1471-2156-5-27