Table 3

APOC3 SstI polymorphism and triglyceride levels

Frequency

Genotype/ Allele

HTG (N = 34)

NTG (N = 105)

Crude OR (95%CI, p value)

Adjusted OR* (95%CI, p value)


Genotype frequency

S1S1

9 (26.5%)

56 (53.3%)

1.00 (Referent)

1.00 (Referent)

S1S2

17 (50%)

44 (41.9%)

2.4 (0.98–5.90, 0.056)

2.43 (0.99–6.01, 0.054)

S2S2

8 (23.5%)

5 (4.8%)

9.95 (2.66–37.29, 0.0006)

9.90 (2.64–37.12, 0.0007)

Allele frequency

S1

0.515 (0.39–0.64)

0.742 (0.68–0.80)

S2

0.485 (0.36–0.61)

0.258 (0.20–0.32)


* Adjusted for age Genotypes: Chi-Square = 14.019, df = 2, p = 0.001; S1S1 vs. S1S2 + S2S2: Chi-Square = 7.445, df = 1, p = 0.006. Alleles: p = 0.001

Chhabra et al. BMC Genetics 2002 3:9   doi:10.1186/1471-2156-3-9

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