Figure 4.

Predicted secondary structure of human "ancestral" TDH protein was determined using the Psi-Pred program and was aligned with that of the crystal structure of uridine diphosphogalactose-4-epimerase protein (GALE) from Escherichia coli[29,31] using 3D-PSSM. The labels are: human "ancestral" TDH protein predicted secondary structure, HsTDH_PSSM; human "ancestral" TDH protein sequence, HsTDH_seq; E. coli GALE protein sequence, EcGale_seq; E. coli GALE protein secondary structure, 1udc_SS; alpha-helix, H, highlighted in light blue; beta-sheet, E, highlighted in yellow; c = turn, coil or loop. Identical residues are shown and additionally, a ":" indicates positive equivalence.

Edgar BMC Genetics 2002 3:18   doi:10.1186/1471-2156-3-18
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