Effect of number of reference haplotypes on imputation accuracy. Average imputation accuracy (IA) as a function of the number of haplotypes in the reference panel used for imputation. Imputation accuracy was estimated for reference panels composed of haplotypes from a trio design (blue triangle), reference panels composed of haplotypes from randomly sampled sires (red circle), and reference panels composed of both haplotypes from a trio design and haplotypes from randomly sampled sires (black circle).
Badke et al. BMC Genetics 2013 14:8 doi:10.1186/1471-2156-14-8