Table 2

Sensitivity analysis
(a). Maternal genotype sensitivity analysis
Study omitted Overall OR Subgroup OR
Women of European descent
Annells et al 2004 0.76 [0.57, 1.01] 0.68 [0.48, 0.95]
Hartel et al 2004 0.73 [0.54, 0.98] 0.63 [0.45, 0.90]
Hollegaard et al 2008 0.72 [0.55, 0.94] 0.65 [0.48, 0.88]
Menon et al 2005 0.73 [0.56, 0.96] 0.66 [0.48, 0.90]
Simhan et al 2003 0.81 [0.63, 1.05] 0.76 [0.57, 1.03]
Stonek et al 2008 0.76 [0.59, 0.99] 0.71 [0.53, 0.94]
Heterogeneous population
Gomez et al 2010 0.74 [0.57, 0.95] 1.01 [0.57, 1.78]
Harper et al 2011 0.74 [0.57, 0.96] 1.08 [0.60, 1.96]
Moura et al 2009 -1 0.73 [0.57, 0.95] 1.00 [0.55, 1.83]
Moura et al 2009 -2 0.74 [0.57, 0.96] 1.06 [0.58, 1.93]
Simhan et al 2003 n/a n/a
Speer EM et al 2006 0.71 [0.54, 0.92] 0.88 [0.43, 1.83]
(b). Fetal genotype sensitivity analysis
Study omitted Overall OR Subgroup OR
Women of European descent
Hartel et al 2004 1.45 [0.63, 3.35] n/a
Heterogeneous population
Pereyra et al 2012 n/a n/a
Speer et al 2006 0.92 [0.66, 1.28] 1.07 [0.12, 9.39]
Velez et al 2007 0.97 [0.71, 1.33] 1.53 [0.61, 3.83]

Wu et al.

Wu et al. BMC Genetics 2013 14:30   doi:10.1186/1471-2156-14-30

Open Data