Table 5

Relative rates of non-synonymous (dN) and synonymous (dS) substitutions with standard errors calculated for the two MHC class IIB loci, averaged over all sites, the peptide binding region (PBR) and non-PBR according to Tong et al.[73]
Positions Locus dN±SE dS±SE dN/dS Z p
All BLB1125 0.14 ± 0.04 0.17 ± 0.05 0.80 -0.61 0.54
BLB2125 0.11 ± 0.04 0.11 ± 0.05 1.00 0.01 0.99
BLB2251 0.11 ± 0.04 0.07 ± 0.02 1.46 1.06 0.29
BLB1&2125 0.12 ± 0.04 0.14 ± 0.05 0.88 -0.33 0.74
PBR BLB1125 0.57 ± 0.22 0.31 ± 0.21 1.84 1.37 0.17
BLB2125 0.53 ± 0.24 0.27 ± 0.20 1.95 1.05 0.30
BLB2251 0.41 ± 0.12 0.16 ± 0.10 2.55 2.16 0.03*
BLB1&2125 0.54 ± 0.20 0.29 ± 0.20 1.84 1.23 0.22
non PBR BLB1125 0.06 ± 0.02 0.14 ± 0.06 0.42 -1.64 0.10
BLB2125 0.04 ± 0.02 0.08 ± 0.04 0.56 -0.85 0.41
BLB2251 0.05 ± 0.01 0.05 ± 0.02 0.92 -0.15 0.88
BLB1&2125 0.05 ± 0.02 0.11 ± 0.04 0.47 -1.58 0.18

Strand et al.

Strand et al. BMC Genetics 2013 14:29   doi:10.1186/1471-2156-14-29

Open Data