Table 4

Positional candidate genes (PCG) within 1-Mb SNP window (SNPW) and their putative functions
Chromosome SNPW PCG Gene ontology
2 19.11 - 19.97 AGPS It encodes a protein that catalyzes the step of lipid biosynthesis
and the removal of long chain acid anion
NFE2L2 It encodes a transcription factor which is a member of a small
family of basic Leucine (bZIP) proteins
2 22.09 - 22.77 WIPF1 It encodes a protein that plays an important role in the organization
of the actin cytoskeleton
OLA1 It hydrolyzes ATP and can hydrolyze GTP with lower efficiency
SP3 regulates transcription by binding consensus GC and GT- box
elements in target genes
12 53.01 - 53.99 SCEL It encodes a tissue-specific basic helix-loop-helix (bHLH) protein
with a pivotal role in hemopoises
EDNRB it mediates actin by association with G-Protein that activates
a phosphaidylinositol-calcium second messenger system
13 14.36 - 14.92 VAMP7 It encodes a transmembrane protein that is a member of soluble
N-ethylmeleimide-sensitive factor attachment protein receptor
(SNARE) family
21 19.00 - 19.98 NTRK3 It encodes a member of a neurotrophic tyrosine receptor kinase family
MIR1179 It involved in post transcriptional regulation of gene expression
MIR7-1 It involved in post transcriptional regulation of gene expression

Kizilkaya et al.

Kizilkaya et al. BMC Genetics 2013 14:23   doi:10.1186/1471-2156-14-23

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