Determination of multilocus genotypes and population structure from Colombian P. falciparum from the Pacific region. A) UPGMA phenogram built with 325 monoclonal samples, using the distance metric 1 - proportion of shared alleles. The labels at the branch tips indicate Colombian parasites MLGs or laboratory controls from MR4. The number in parenthesis shows the number of identical parasites within a MLG (n = 136) and the colors of the branches indicate the four populations identified by the program STRUCTURE. B) Plot of Var [LnP(D)] vs. K probability showing the best K subpopulation partition at K = 4; for complementary information see Additional file 3. C) Output from STRUCTURE software. Each MLG is represented by a vertical line and each color represents a different subpopulation; many MLGs showed mixed ancestry (length of the colored lines indicate the estimated proportion of membership of each MLG to that subpopulation). D) Distribution of the four subpopulations across the provinces at the Colombian Pacific region. The frequency of each subpopulation is shown as a percentage.
Echeverry et al. BMC Genetics 2013 14:2 doi:10.1186/1471-2156-14-2