Table 3

Summary of cohort results
Mongolian Korean CEPH families
Number of SNP markers 569132 516452 931633
Meioses 254 722 234
Total crossovers detected 8776 24355 8093
Average male recombination rate 27.43 25.84 26.49
Average female recombination rate 41.96 40.75 42.90
Median resolution (bp) 83525 114681 74169
Historical hotspot concordance 0.83 0.81 0.82
Concordance of randomly placed intervals 0.36 0.37 0.35
Estimated true historical hotspot usage 0.74 0.70 0.72

Summary of results for the three cohorts. We do not find the differences in recombination rate or historical hotspot concordance significant. Historical hotspot concordance records the overlap rate of crossovers resolved to 30 kb or better. ‘Randomly placed intervals’ are generated by random perturbations of well-resolved crossovers following a normal distribution (μ = 0; σ = 200 kb). The Mongolian and Korean results were combined to form our Asian genetic map.

Bleazard et al.

Bleazard et al. BMC Genetics 2013 14:19   doi:10.1186/1471-2156-14-19

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