Table 1

Estimates of false discovery rate
Analysis SI SII SIII
(trait) LOD-d 1% 5% 10% 1% 5% 10% 1% 5% 10%
MIM 1.0 9.1 9.1 9.9 8.9 9.2 10.0 7.2 7.9 8.7
(T1) 1.5 3.9 4.4 5.3 3.7 4.3 5.3 2.8 3.5 4.1
2.0 2.0 2.7 3.6 1.8 2.2 3.0 1.4 1.9 2.3
MIM 1.0 8.0 8.7 8.9 7.9 8.6 9.6 6.2 7.0 7.8
(T2) 1.5 3.9 4.2 4.7 3.2 4.1 5.4 3.1 3.7 4.5
2.0 2.0 2.3 3.0 1.2 2.2 3.6 1.2 2.1 2.8
MIM 1.0 10.7 9.6 9.9 12.4 13.8 18.0
(T3) 1.5 3.8 4.2 4.9 7.5 9.0 11.4
2.0 1.8 2.3 3.1 4.8 6.5 8.5
MTMIM 1.0 4.6 5.4 6.9 8.5 9.2 10.0 5.6 7.8 8.4
1.5 1.9 2.7 4.0 3.3 4.1 4.9 2.9 5.2 5.7
2.0 1.1 1.9 3.3 1.4 2.4 3.2 2.2 4.1 4.5

Estimates of FDR (%) in the MIM and MTMIM models as observed in scenarios SI, SII and SIII across genome-wide significance levels (1, 5 and 10%) and LOD-d support intervals.

Costa E Silva et al.

Costa E Silva et al. BMC Genetics 2012 13:67   doi:10.1186/1471-2156-13-67

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