Figure 1.

Relation between a vQTL and an epistatic interaction. Panel (a) plots phenotype values in arbitrary units for a population of 500 outbred individuals stratified by genotype at a hypothetical vQTL. Panel (b) shows how the pattern in (a) could have arisen through a simple (mean-controlling) epistatic interaction with a second locus, possibly on another chromosome, that segregates two genotypes (black and gray).

Rönnegård and Valdar BMC Genetics 2012 13:63   doi:10.1186/1471-2156-13-63
Download authors' original image