L2E and MLE mapping of the mice data. Genomic scanning profiles for mapping QTLs controlling the growth rate of body mass from weeks 5 to 10 by L2E (a) and ML approaches (b). The y-axes are the ED and LR test statistics, respectively. The dash dot line and the dash line are the chromosome-wide and genome-wide 0.05 cutoffs at the significant level of 0.05 based on the 1000 permutations, respectively. The x-axis ticks indicates the marker positions, the arrows to the × axes shows the genomic positions of the significant QTL at chromosome level, and the asterisk at chromosome 8 in the L2E profile marks a genome-wide significant QTL.
Wu et al. BMC Genetics 2012 13:20 doi:10.1186/1471-2156-13-20