Open Access Research article

Diversity of metalloproteinases in Bothrops neuwiedi snake venom transcripts: evidences for recombination between different classes of SVMPs

Ana M Moura-da-Silva1*, Maria Stella Furlan1, Maria Cristina Caporrino1, Kathleen F Grego2, José Antonio Portes-Junior1, Patrícia B Clissa1, Richard H Valente3 and Geraldo S Magalhães1

Author Affiliations

1 Laboratório de Imunopatologia, Instituto Butantan, São Paulo, São Paulo, Brazil

2 Laboratório de Herpetotologia, Instituto Butantan, São Paulo, São Paulo, Brazil

3 Laboratório de Toxinologia, Instituto Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil

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BMC Genetics 2011, 12:94  doi:10.1186/1471-2156-12-94

Published: 1 November 2011

Additional files

Additional file 1:

Sequence alignment of cDNAs encoding B. neuwiedi SVMPs. Complete cDNA sequences were aligned using the Blastn program for multiple sequences alignments using as query BnMP-III1 sequence: (.) identical nucleotides to the first sequence; (-) gaps introduced to maximize sequence alignments; regions coding for functional motifs as the zinc-bindin residues and RGD disintegrin tripeptide are boxed; alignments of complementary (-) or repeated (+) regions in relation to BnMP-III1 sequence are highlighted in gray.

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Additional file 2:

Sequence alignment of cDNAs encoding BnMP-I1, BnMP-I2 and BnMP-IIa. Complete cDNA sequences were aligned using the Blastn program for multiple sequences alignments using as query BnMP-I1 sequence: (.) identical nucleotides to the first sequence. Note the absence of disintegrin domain coding region in BnMP-I1 and BnMP-I2 sequences.

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Open Data