Table 2 

Distribution of IL12B 3' UTR genotypes in children with P. falciparum malaria 

IL12B 3' UTR Genotypes 
NonSMA 
SMA 
P^{a} 


No. of participants, n 
304 
240 

AA 
132 (43.4) 
82 (34.2) 

AC 
123 (40.5) 
104 (43.3) 
0.048 
CC 
49 (16.1) 
54 (22.5) 

P(A) = 0.64 
P(A) = 0.56 



Data are presented as proportion of individuals [n (%)] within nonSMA and SMA groups. Children with P. falciparum malaria (n = 544) were categorized according to SMA status based on age and geographicallyappropriate Hb concentrations [i.e., Hb<6.0 g/dL, with any density parasitaemia) [4]] and nonSMA (Hb≥6.0 g/dL, with any density parasitaemia). ^{a}Statistical significance determined by Chisquare analysis. The overall distribution of genotypes between the nonSMA and SMA groups was statistically significant (χ^{2 }test, P = 0.048). 

Ong'echa et al. BMC Genetics 2011 12:69 doi:10.1186/147121561269 