Additional file 4.

Variance inflation under relatedness. Comparison of the theoretical variance of the β1-estimator assuming uncorrelated phenotypes (analytical formula ) with the averaged variances over all SNPs of chromosome 22 under a heritability of 100% assuming correlated phenotypes. The standard error of this estimate and the inflation factor are also provided. Sorbs977 are presented in bold due to high inflation of variances of β1-estimates.

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Gross et al. BMC Genetics 2011 12:67   doi:10.1186/1471-2156-12-67