Table 5 |
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Scenarios that could occur across the genome with the optimal method of selection. |
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Structured Phenotype (K1 ≠ K2) |
Non-Structured Phenotype (K1 = K2) |
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|
|
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Structured Genotype (p1≠ p2) |
Any method of selection except no PC adjustment |
Selecting a fixed number of PCs or PCs associated with the SNP |
|
|
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Non-Structured Genotype (p1 = p2) |
Selecting PCs associated with the SNP (α = 0.01), 10% Rule, no PC adjustment |
Any method of selection |
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|
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p1 and p2 are the allele frequencies in population 1 and 2, respectively. K1 and K2 are the frequency of disease in population 1 and 2, respectively. |
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Peloso and Lunetta BMC Genetics 2011 12:64 doi:10.1186/1471-2156-12-64 |
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