Geographic Differences in the Allelic Frequencies of a FADS Gene Cluster SNP. Geographic distribution (a) of derived allele frequencies (shown in orange) for rs174537 in the 52 populations represented in the Human Genome Diversity Panel Data. The data suggest the fixation of derived rs174537 G allele within the African continent. Similarly, the continental distribution for rs174537 genotypes (b) shows a dramatic shift in the predominant homozygous state from Africa to the Americas.
Mathias et al. BMC Genetics 2011 12:50 doi:10.1186/1471-2156-12-50