Table 1

Penetrance values for simulation settings

additive model

dominant model

recessive model


104 × f0

104 × f1

104 × f2

104 × f0

104 × f1

104 × f2

104 × f0

104 × f1

104 × f2


r = 3

p = 0.1

71

214

357

72

217

217

98

98

294

p = 0.25

50

150

250

53

160

160

89

89

267

p = 0.5

33

100

167

40

120

120

67

67

200

r = 2.5

p = 0.1

77

192

308

78

195

195

99

99

246

p = 0.25

57

143

229

60

151

151

91

91

229

p = 0.5

40

100

160

47

118

118

73

73

182

r = 2

p = 0.1

83

167

250

84

168

168

99

99

198

p = 0.25

67

133

200

70

139

139

94

94

188

p = 0.5

50

100

150

57

114

114

80

80

160


Numbers listed are scaled penetrance values (104 × f0, 104 × f1, 104 × f2) corresponding to different allele frequencies (p) and relative ratios (r) under three genetic models

The prevalence K is set at 0.01

Lee et al. BMC Genetics 2011 12:48   doi:10.1186/1471-2156-12-48

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