Table 3 

Number of significant interactions in the subpopulations in the Supine model 

Partition: 
model with covariates 
Supine model without covariates 



Trait: 
Systolic 
Diastolic 
Systolic 
Diastolic 



Subpopulations 
No cases 
Interactions 
Fraction 
Interactions 
Fraction 
No cases 
Interactions 
Fraction 
Interactions 
Fraction 



1 
39 
307 
32,49% 
307 
32,49% 
27 
331 
35,03% 
306 
32,38% 



2 
111 
318 
33,65% 
316 
33,44% 
113 
325 
34,39% 
325 
34,39% 



3 
259 
298 
31,53% 
294 
31,11% 
625 
323 
34,18% 
335 
35,45% 



4 
33 
230 
24,34% 
334 
35,34% 
104 
338 
35,77% 
338 
35,77% 



5 
189 
257 
27,20% 
257 
27,20% 
1 
0 
0,00% 
0 
0,00% 



6 
301 
321 
33,97% 
310 
32,80% 
30 
320 
33,86% 
320 
33,86% 



7 
132 
306 
32,38% 
307 
32,49% 
23 
262 
27,72% 
332 
35,13% 



8 
89 
238 
25,19% 
238 
25,19% 
89 
304 
32,17% 
305 
32,28% 



9 
237 
275 
29,10% 
276 
29,21% 
332 
231 
24,44% 
238 
25,19% 



10 
141 
334 
35,34% 
337 
35,66% 
279 
295 
31,22% 
295 
31,22% 



11 
163 
295 
31,22% 
302 
31,96% 
7 
0 
0,00% 
0 
0,00% 



12 
40 
336 
35,56% 
336 
35,56% 
544 
226 
23,92% 
232 
24,55% 



13 
166 
307 
32,49% 
306 
32,38% 
73 
285 
30,16% 
285 
30,16% 32,28% 



14 
21 
174 
18,41% 
148 
15,66% 
19 
159 
16,83% 
305 





Sum 
1.921 
3.996 
4.068 
2.266 
3.399 
3.616 



Average 
285,43 
30,20% 
290,57 
30,75% 
242,79 
25,69% 
258,29 
27,33% 



Variance 
2.115 
2.498 
13.074 
13.012 



Average Total 
30,20% 
30,75% 
25,69% 
27,33% 



Minimum 
21 
174 
18,41% 
148 
15,66% 
1 
0 
0,00% 
0 
0,00% 



Maximum 
301 
336 
35,56% 
337 
35,66% 
625 
338 
35,77% 
338 
35,77% 





Systolic versus diatolic blood pressure^{b} 
Number of interactions 
Number of interactions 



pvalue 
0,78 
0,72 





Supine model with and without covariates^{c} 



Systolic 
Diastolic 



Ftest 
pvalue 
0,0024 
0,0055 





Number of total interactions detected 
Full model 
Model without covariates 



Interactions 
Fraction 
Interactions 
Fraction 



Systolic 
676 
68,28% 
695 
70,20% 



Diastolic 
681 
68,79% 
695 
70,20% 



a The fraction is calculated as the number of significant interactions detected realtive to the maximal number of interaction possible b Test of difference in number of interactions between diastolic and systolic blood pressures c Test of the number of significant interactions in the two models. The number of interactions in the model with covariates (the fulle model) is significant higher than in the resticted model without covariates. 

Fenger et al. BMC Genetics 2011 12:44 doi:10.1186/147121561244 