Open Access Highly Accessed Research article

Candidate genes for idiopathic epilepsy in four dog breeds

Kari J Ekenstedt1*, Edward E Patterson1, Katie M Minor2 and James R Mickelson2

Author Affiliations

1 Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, 1352 Boyd Avenue, Saint Paul, Minnesota, 55108, USA

2 Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, 295 AS/VM, 1988 Fitch Avenue, St. Paul, Minnesota, 55108, USA

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BMC Genetics 2011, 12:38  doi:10.1186/1471-2156-12-38

Published: 25 April 2011

Additional files

Additional file 1:

Primer sequences for candidate gene microsatellites. Sequence information and product sizes are presented for primers designed for microsatellites examined for each candidate gene. Bolded genes marked with a * indicate those associated with human epilepsy, and bolded genes marked with a # indicate those associated with mouse models of epilepsy. Two of the DNM1 marker primer pairs, DNM1 Third Set and DNM1 Fifth Set, are taken from the University of California-Davis Canine Genetic Linkage Map [74], and are named therein 0945 and 0946, respectively. CFA = canis familiaris chromosome.

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Additional file 2:

Candidate gene locations and primer locations. All pertinent canine chromosomal location information is presented for each gene and all microsatellites examined for that gene. Bolded genes marked with a * indicate those associated with human epilepsy, and bolded genes marked with a # indicate those associated with mouse models of epilepsy. Two of the DNM1 marker primer pairs, DNM1 Third Set and DNM1 Fifth Set, are taken from the University of California-Davis Canine Genetic Linkage Map [74], and are named therein 0945 and 0946, respectively. ^ Bolded entries in this column indicate microsatellites located outside the gene itself and further than 1 Mb away (n = 3). Mb positions given for microsatellites are the first nucleotide of each microsatellite. Mb positions were taken from Ensembl [75] and the UCSC Genome Browser [61]. CFA = canis familiaris chromosome.

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