Table 2

Allelic associations

MCP1

allele

cases n (frequency)

controls n (frequency)

OR

CI

Pnom

Pcorr


-97569

C

1497 (0.38)

1745 (0.38)

1

0.99

G

2471 (0.62)

2889 (0.62)

1.00

[0.92-1.09]

-38600

T

1730 (0.44)

2107 (0.46)

1

C

2228 (0.56)

2463 (0.54)

1.10

[1.01-1.20]

0.031

-2581*

A

3256 (0.83)

3692 (0.80)

1

G

672 (0.17)

932 (0.20)

0.81

[0.73-0.91]

0.0002

0.0012

-1727

A

113 (0.03)

149 (0.03)

1

T

3525 (0.97)

4133 (0.97)

1.14

[0.88-1.45]

0.32

-362*

G

2266 (0.58)

2441 (0.53)

1

C

1670 (0.42)

2161 (0.47)

0.83

[0.76-0.90]

0.000019

0.00015

Int1:96

C

967 (0.29)

1092 (0.26)

1

G

2401 (0.71)

3128 (0.74)

0.87

[0.78-0.96]

0.0055

Int1:554-567

W

2432 (0.61)

2646 (0.57)

1

D

1586 (0.39)

2028 (0.43)

0.85

[0.78-0.92]

0.00014

0.00098

+1542

T

711 (0.18)

933 (0.20)

1

C

3291 (0.82)

3745 (0.80)

1.16

[1.04-1.29]

0.008

+2413

T

134 (0.07)

198 (0.07)

1

G

1750 (0.93)

2652 (0.93)

0.97

[0.77-1.22]

0.81

+2580

A

397 (0.10)

454 (0.10)

1

T

3591 (0.90)

4184 (0.90)

0.97

[0.84-1.12]

0.71


OR, odds ratio; CI, 95% confidence interval; P values are adjusted for age, gender and ethnicity;

Pnom, nominal P value; Pcorr, P value after Bonferroni-Holm correction; *variants -2581 and -362 were originally genotyped and described in Ref. [15]; Int1, intron 1; D, deletion; W, wildtype

Intemann et al. BMC Genetics 2011 12:34   doi:10.1186/1471-2156-12-34

Open Data