Resolution:
## Figure 3.
Empirical type I error observed when self-reported ethnicity (assuming no misclassification
error) and individual ancestry proportion are respectively used as control variables
in the association test. Figure 3a shows the effect of the gap in the distribution of individual admixture
on type I error rate when controlling for admixture and ethnicity when the effect
size is equal to 0.5. One can observe on figure 3a that there is a slight type I
error inflation even when true ethnicity is used instead of the true ancestry proportion.
This inflation decreases as the gap in the admixture distribution increases. The admixture
distribution in this case is univariate as would be observed for an admixed population
derived from intermating between exactly 2 ancestral populations. Figure 3b shows
higher type I error inflation rate when the effect size is equal to 1.
Divers |