Table 2

Obesity traits in five subcongenics and their parental strains on low-fat standard chow diet

Sex

Strain

n

Body weight (g)

Lean body weight (g)

Inguinal fat pad weight (g)

Gonadal fat pad weight (g)

Retroperitoneal fat pad weight (g)

Total fat pad weight (g)

Adiposity index


Male

B6

45

27.28 ± 0.051

26.23 ± 0.048

0.455 ± 0.005

0.424 ± 0.003

0.164 ± 0.003

1.043 ± 0.009

0.038 ± 0.0003

B6.Cg-Pbwg1

40

26.83 ± 0.063

26.04 ± 0.061

0.336 ± 0.003***

0.338 ± 0.003***

0.116 ± 0.002***

0.790 ± 0.004***

0.031 ± 0.0007***

B6.Cg-Pbwg1/SR13

15

27.69 ± 0.057

26.90 ± 0.056

0.345 ± 0.006**

0.308 ± 0.006***

0.132 ± 0.004

0.785 ± 0.014***

0.035 ± 0.0008***

B6.Cg-Pbwg1/SR12

30

29.00 ± 0.115**

28.07 ± 0.108**

0.393 ± 0.007*

0.390 ± 0.007

0.149 ± 0.003

0.933 ± 0.014*

0.028 ± 0.0008***

B6.Cg-Pbwg1/SR8

39

26.13 ± 0.055*

25.49 ± 0.054*

0.293 ± 0.004***

0.265 ± 0.003***

0.082 ± 0.002***

0.641 ± 0.007***

0.030 ± 0.0014***

B6.Cg-Pbwg1/SR3

16

27.22 ± 0.039

26.19 ± 0.036

0.439 ± 0.003

0.453 ± 0.003

0.176 ± 0.004

1.029 ± 0.009

0.031 ± 0.0001

B6.Cg-Pbwg1/SR4

23

28.01 ± 0.172

26.89 ± 0.157

0.466 ± 0.011

0.470 ± 0.006

0.191 ± 0.007

1.128 ± 0.022

0.034 ± 0.0011


Female

B6

39

21.96 ± 0.044

21.17 ± 0.043

0.359 ± 0.002

0.296 ± 0.002

0.136 ± 0.001

0.791 ± 0.003

0.036 ± 0.0002

B6.Cg-Pbwg1

31

21.24 ± 0.056**

20.63 ± 0.052**

0.266 ± 0.002***

0.234 ± 0.002***

0.108 ± 0.001***

0.608 ± 0.004***

0.029 ± 0.0002***

B6.Cg-Pbwg1/SR13

14

21.03 ± 0.055

20.48 ± 0.053

0.268 ± 0.001***

0.175 ± 0.003***

0.104 ± 0.001*

0.547 ± 0.005***

0.026 ± 0.0003***

B6.Cg-Pbwg1/SR12

30

22.33 ± 0.066

21.55 ± 0.061

0.366 ± 0.003

0.278 ± 0.004

0.130 ± 0.002

0.774 ± 0.005

0.034 ± 0.0002

B6.Cg-Pbwg1/SR8

31

20.02 ± 0.050***

19.59 ± 0.049***

0.233 ± 0.003***

0.129 ± 0.002***

0.063 ± 0.001***

0.425 ± 0.004***

0.021 ± 0.0002***

B6.Cg-Pbwg1/SR3

14

21.81 ± 0.066

21.12 ± 0.067

0.344 ± 0.002

0.289 ± 0.002

0.147 ± 0.001

0.780 ± 0.005

0.036 ± 0.0003

B6.Cg-Pbwg1/SR4

27

22.14 ± 0.046

21.36 ± 0.041

0.375 ± 0.005

0.288 ± 0.005

0.112 ± 0.002*

0.776 ± 0.006

0.035 ± 0.0002


Data are least-squared means ± SE at 13 weeks of age. n, number of mice. Sex separated data were analyzed with a linear mixed model (see Materials and Methods) and fat pad weights were not adjusted for lean body weight. Total fat pad weight is the sum of the three fat pad weights. Adiposity index was calculated by dividing total fat pad weight by body weight. The mean with stars (*, P < 0.05; **, P < 0.01; ***, P < 0.001) within the same sex is significantly different from that of B6 (Dunnett's test).

Mollah and Ishikawa BMC Genetics 2010 11:84   doi:10.1186/1471-2156-11-84

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