Table 2

Prediction rate of combinations of SNPs with genotype-based p-value filtering

p-value range

No. of SNPs [1]

Prediction rate

No. of SNPs [2]


Overall

Sensitivity

Specificity


< 0.05

24

0.576

0.545

0.607

4 SNPs

< 0.1

40

0.600

0.593

0.607

6 SNPs

< 0.2

92

0.632

0.660

0.603

10 SNPs

< 0.3

129

0.642

0.630

0.654

12 SNPs

< 0.4

169

0.642

0.630

0.654

12 SNPs

< 0.5

199

0.651

0.571

0.732

13 SNPs

< 0.6

240

0.653

0.567

0.739

14 SNPs

< 0.7

290

0.651

0.610

0.693

12 SNPs

< 0.8

335

0.636

0.721

0.550

7 SNPs

< 0.9

372

0.636

0.721

0.550

7 SNPs

<1.0

408

0.636

0.721

0.550

7 SNPs


[1] No. of SNPs for each genotype-based p-value range; [2] No. of SNPs for each combination

Ban et al. BMC Genetics 2010 11:26   doi:10.1186/1471-2156-11-26

Open Data