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Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and non-Hispanic whites

Josiemer Mattei12, Laurence D Parnell1, Chao-Qiang Lai1, Bibiana Garcia-Bailo3, Xian Adiconis4, Jian Shen1, Donna Arnett5, Serkalem Demissie6, Katherine L Tucker12 and Jose M Ordovas12*

Author Affiliations

1 Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA

2 Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA

3 Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

4 Genome Biology and Cell Circuits Program, Broad Institute, Cambridge, MA, USA

5 Department of Epidemiology, University of Alabama, Birmingham, Birmingham, AL, USA

6 Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA

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BMC Genetics 2009, 10:45  doi:10.1186/1471-2156-10-45

Published: 14 August 2009

Additional files

Additional file 1:

Gene and genotyping information for 101 SNPs genotyped in Puerto Rican and non-Hispanic white subjects. Gene variant name, location, function, reference number and the corresponding genotyping primer, probe or assay-on-demand ID for 101 SNPs genotyped in Puerto Rican and non-Hispanic white subjects.

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Additional file 2:

Allele and genotype frequencies for 101 SNPs in Puerto Ricans and non-Hispanic whites.

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Additional file 3:

Predicted minor allele frequencies, and measures of population differentiation for Puerto Ricans and non-Hispanic whites. Predicted minor allele frequencies under an admixture model, and measures of population-specific and between-population differentiation for Puerto Ricans and non-Hispanic whites.

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