Figure 4.

Four causal inference strategies, CC, CIT, BNC, and AIC were applied to simulated data under five distinct causal models, A-E, shown above. Here a genotype marker at a specific locus is denoted by L, a gene corresponding to measured transcript abundance is denoted by G, and a measured clinical trait is denoted by T. H denotes an unmeasured molecular trait.

Millstein et al. BMC Genetics 2009 10:23   doi:10.1186/1471-2156-10-23
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