Open Access Highly Accessed Research article

High-resolution haplotype block structure in the cattle genome

Rafael Villa-Angulo1*, Lakshmi K Matukumalli13, Clare A Gill2, Jungwoo Choi2, Curtis P Van Tassell3 and John J Grefenstette1

Author Affiliations

1 Department of Bioinformatics and Computational Biology, George Mason University, VA, USA

2 Department of Animal Science, Texas A&M University, College Station, TX, USA

3 Bovine Functional Genomics Laboratory, USDA-ARS, Beltsville, MD, USA

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BMC Genetics 2009, 10:19  doi:10.1186/1471-2156-10-19

Published: 24 April 2009

Additional files

Additional file 1:

Breeds and number of animals in the sample.

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Additional file 2:

Structural details of the 101 high-density regions selected on chromosomes 6, 14 and 25.

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Additional file 3:

MAF distribution. Average proportions of SNPs of various frequencies by breed in high-density regions (intervals' upper limit inclusive).

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Additional file 4:

Average minor allele frequencies (MAF) per breed across the high density regions in this study.

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Additional file 5:

Total average of r2 per breed across high density regions.

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Additional file 6:

Effective population size for each breed, estimated from r2.

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Additional file 7:

Haplotype block structure across high-density regions in all breeds.

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